Influential Papers that Shaped Paradigms and Changed Practice in Infection Prevention in the Last 60 Years: Then, Now, and Future Directions

Laura Pedersen, Gonzalo Bearman, Martin Kiernan, Mark E. Rupp

Research output: Contribution to journalReview articlepeer-review

Abstract

Purpose of Review: Advancements in infection prevention reduce morbidity and mortality in hospitalized patients. We recognize the authors and publications with substantial impact on health care epidemiology and clinical practice in the last 60 years. Recent Findings: Substantial advancements in infection prevention include hand hygiene monitoring and feedback, prevention of central line-associated bloodstream infections, the use of chlorhexidine patient bathing, transmission-based precautions and improved environmental cleaning. Advancements in technology, including whole genome sequencing and hand hygiene sensor badges, may improve infection prevention efforts. While improvements in study design are necessary in infection prevention to best guide practice, current nosocomial infection prevention efforts are generally a cost-effective investment for healthcare systems. Summary: Advancements in healthcare epidemiology over the last 60 years improved patient outcomes in hospital settings. Future well-designed studies are required, with a focus on implementation science and evolving technologies, to better define effective infection prevention strategies.

Original languageEnglish (US)
Pages (from-to)29-37
Number of pages9
JournalCurrent Infectious Disease Reports
Volume24
Issue number2
DOIs
StatePublished - Feb 2022

Keywords

  • Decolonization
  • Hand hygiene
  • Hospital-acquired infections
  • Infection control
  • Transmission-based precautions

ASJC Scopus subject areas

  • Infectious Diseases

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