Innovations and recent trends in the treatment of ADHD

Vishal Madaan; Shannon Kinnan; Joan Daughton; Christopher J. Kratochvil

doi:10.1586/14737175.6.9.1375

Innovations and recent trends in the treatment of ADHD

Vishal Madaan, Shannon Kinnan, Joan Daughton, Christopher J. Kratochvil

Research output: Contribution to journal › Review article › peer-review

19 Scopus citations

Abstract

Initiatives to develop better-tolerated, more efficacious pharmacological agents with improved drug delivery systems have driven recent research in attention-deficit hyperactivity disorder (ADHD). While stimulants are the primary pharmacotherapy for ADHD, these drugs have a limited duration of action and a subset of patients will either fail to respond to these medications or have side effects that preclude their use. The development of atomoxetine, the first nonstimulant approved for ADHD, has been followed by additional innovative research, such as the methylphenidate transdermal system, modafinil, NRP-104 and cholinergic agents. This review highlights some of the recent trends in ADHD treatment and the current status of promising treatment options that may help to shape the future of ADHD treatment.

Original language	English (US)
Pages (from-to)	1375-1385
Number of pages	11
Journal	Expert Review of Neurotherapeutics
Volume	6
Issue number	9
DOIs	https://doi.org/10.1586/14737175.6.9.1375
State	Published - Sep 2006

Keywords

Atomoxetine
Attention-deficit hyperactivity disorder
Modafinil
NRP-104
Pharmacotherapy
Stimulants
Transdermal

ASJC Scopus subject areas

General Neuroscience
Clinical Neurology
Pharmacology (medical)

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10.1586/14737175.6.9.1375

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abstract = "Initiatives to develop better-tolerated, more efficacious pharmacological agents with improved drug delivery systems have driven recent research in attention-deficit hyperactivity disorder (ADHD). While stimulants are the primary pharmacotherapy for ADHD, these drugs have a limited duration of action and a subset of patients will either fail to respond to these medications or have side effects that preclude their use. The development of atomoxetine, the first nonstimulant approved for ADHD, has been followed by additional innovative research, such as the methylphenidate transdermal system, modafinil, NRP-104 and cholinergic agents. This review highlights some of the recent trends in ADHD treatment and the current status of promising treatment options that may help to shape the future of ADHD treatment.",

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author = "Vishal Madaan and Shannon Kinnan and Joan Daughton and Kratochvil, {Christopher J.}",

note = "Funding Information: Christopher J Kratochvil is supported by NIMH Grant 5K23MH06612701A1. He also receives grant support from Eli Lilly (IN, USA), McNeil (NJ, USA) and Cephalon (PA, USA), is a consultant for Eli Lilly, Shire (PA, USA), Cephalon, Organon (NJ, USA), AstraZeneca (DE, USA), Boehringer-Ingel-heim (Germany) and Pfizer (NY, USA), and a member of the Eli Lilly speaker{\textquoteright}s bureau.",

year = "2006",

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doi = "10.1586/14737175.6.9.1375",

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Innovations and recent trends in the treatment of ADHD

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Keywords

ASJC Scopus subject areas

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