Abstract
Human β-defensins 2 and 3 are small cationic peptides with antimicrobial activity against the fungal pathogen Candida albicans. We found that hog1 and pbs2 mutants were hypersensitive to treatment with these peptides, pointing to a role of the high-osmolarity glycerol (HOG) pathway in the response to defensin-induced cell injury.
Original language | English (US) |
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Pages (from-to) | 272-275 |
Number of pages | 4 |
Journal | Eukaryotic Cell |
Volume | 10 |
Issue number | 2 |
DOIs |
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State | Published - Feb 2011 |
Externally published | Yes |
ASJC Scopus subject areas
- Microbiology
- Molecular Biology