Intergenerational associations of adverse birth outcomes: A surveillance report

Dong Liu; Ge Lin; Dejun Su; James M. Alexender; Xiaoting Sun; Ming Qu

doi:10.1016/j.pmedr.2020.101226

Intergenerational associations of adverse birth outcomes: A surveillance report

Dong Liu, Ge Lin, Dejun Su, James M. Alexender, Xiaoting Sun, Ming Qu

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5 Scopus citations

Abstract

Nebraska births between 1995 and 2005 were followed until 2018 to look for intergenerational associations of low birth weight (LBW) and preterm birth (PTB). Results from generalized estimating equations revealed that mothers born LBW preterm were more likely to deliver LBW (adjusted OR 1.94, 95% CI 1.39–2.71) or preterm (adjusted OR 1.65, 95% CI 1.20–2.27) than mothers born with normal weight or at term. In addition, mothers who had an LBW sibling were 44% more likely to have an LBW infant (OR 1.44, 95% CI 1.04–2.00). A consistent finding was also observed for mothers who had a PTB sibling (OR 1.47, 95% CI 1.10–1.95). Mothers who were LBW at birth or had any LBW siblings, especially two or more siblings, were more likely to repeat this adverse birth outcome. The same association was also observed in mothers who were born preterm.

Original language	English (US)
Article number	101226
Journal	Preventive Medicine Reports
Volume	20
DOIs	https://doi.org/10.1016/j.pmedr.2020.101226
State	Published - Dec 2020

Keywords

Birth history
Intergenerational associations
Low birthweight
Preterm birth
Recurrence
Siblings
Vital statistics

ASJC Scopus subject areas

Health Informatics
Public Health, Environmental and Occupational Health

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10.1016/j.pmedr.2020.101226

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title = "Intergenerational associations of adverse birth outcomes: A surveillance report",

abstract = "Nebraska births between 1995 and 2005 were followed until 2018 to look for intergenerational associations of low birth weight (LBW) and preterm birth (PTB). Results from generalized estimating equations revealed that mothers born LBW preterm were more likely to deliver LBW (adjusted OR 1.94, 95% CI 1.39–2.71) or preterm (adjusted OR 1.65, 95% CI 1.20–2.27) than mothers born with normal weight or at term. In addition, mothers who had an LBW sibling were 44% more likely to have an LBW infant (OR 1.44, 95% CI 1.04–2.00). A consistent finding was also observed for mothers who had a PTB sibling (OR 1.47, 95% CI 1.10–1.95). Mothers who were LBW at birth or had any LBW siblings, especially two or more siblings, were more likely to repeat this adverse birth outcome. The same association was also observed in mothers who were born preterm.",

keywords = "Birth history, Intergenerational associations, Low birthweight, Preterm birth, Recurrence, Siblings, Vital statistics",

author = "Dong Liu and Ge Lin and Dejun Su and Alexender, {James M.} and Xiaoting Sun and Ming Qu",

note = "Publisher Copyright: {\textcopyright} 2020 The Authors",

year = "2020",

month = dec,

doi = "10.1016/j.pmedr.2020.101226",

language = "English (US)",

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journal = "Preventive Medicine Reports",

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AU - Liu, Dong

AU - Lin, Ge

AU - Su, Dejun

AU - Alexender, James M.

AU - Sun, Xiaoting

AU - Qu, Ming

PY - 2020/12

Y1 - 2020/12

N2 - Nebraska births between 1995 and 2005 were followed until 2018 to look for intergenerational associations of low birth weight (LBW) and preterm birth (PTB). Results from generalized estimating equations revealed that mothers born LBW preterm were more likely to deliver LBW (adjusted OR 1.94, 95% CI 1.39–2.71) or preterm (adjusted OR 1.65, 95% CI 1.20–2.27) than mothers born with normal weight or at term. In addition, mothers who had an LBW sibling were 44% more likely to have an LBW infant (OR 1.44, 95% CI 1.04–2.00). A consistent finding was also observed for mothers who had a PTB sibling (OR 1.47, 95% CI 1.10–1.95). Mothers who were LBW at birth or had any LBW siblings, especially two or more siblings, were more likely to repeat this adverse birth outcome. The same association was also observed in mothers who were born preterm.

AB - Nebraska births between 1995 and 2005 were followed until 2018 to look for intergenerational associations of low birth weight (LBW) and preterm birth (PTB). Results from generalized estimating equations revealed that mothers born LBW preterm were more likely to deliver LBW (adjusted OR 1.94, 95% CI 1.39–2.71) or preterm (adjusted OR 1.65, 95% CI 1.20–2.27) than mothers born with normal weight or at term. In addition, mothers who had an LBW sibling were 44% more likely to have an LBW infant (OR 1.44, 95% CI 1.04–2.00). A consistent finding was also observed for mothers who had a PTB sibling (OR 1.47, 95% CI 1.10–1.95). Mothers who were LBW at birth or had any LBW siblings, especially two or more siblings, were more likely to repeat this adverse birth outcome. The same association was also observed in mothers who were born preterm.

KW - Birth history

KW - Intergenerational associations

KW - Low birthweight

KW - Preterm birth

KW - Recurrence

KW - Siblings

KW - Vital statistics

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ER -

Intergenerational associations of adverse birth outcomes: A surveillance report

Abstract

Keywords

ASJC Scopus subject areas

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