Intramedullary PNET of the spine: Long-term survival after combined modality therapy and subsequent relapse

Russell P. Gollard, Larry Rosen, John Anson, James Mason, Joe Khoury

Research output: Contribution to journalArticlepeer-review

10 Scopus citations

Abstract

Primitive neuroectodermal tumors (PNET) originating within the spinal cord are extraordinarily rare. We report a female who presented at age 21 with diffuse involvement of the lower spinal cord. After biopsy and successful treatment with radiation and chemotherapy, she recurred 10 years later with disease in her cerebellum. She was reinduced with chemotherapy and subsequently received high-dose chemotherapy with autologous stem cell support. She is alive and free of disease 11 years after her initial presentation. This represents the longest survival ever documented for a primary spinal PNET.

Original languageEnglish (US)
Pages (from-to)107-112
Number of pages6
JournalJournal of Pediatric Hematology/Oncology
Volume33
Issue number2
DOIs
StatePublished - Mar 2011
Externally publishedYes

Keywords

  • neoplasm of spine
  • neuroectodermal tumors
  • pediatric medulloblastoma protocol

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology

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