Intrathecal drug therapy: General considerations

Jaroslaw S. Przybyl, Kenneth A. Follett, David Caraway

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Intrathecal drug-delivery systems have been used increasingly for management of pain and spasticity. The indications, efficacy, and cost-effectiveness of intrathecal therapy have not been established with certainty in randomized, controlled trials, but most available data indicate that intrathecal therapy can be a remarkably useful treatment of otherwise intractable pain and spasticity. Outcomes will undoubtedly improve further as we gain a better understanding of (and strict adherence to) patient selection criteria and mechanisms governing intrathecal drug actions while continuing to emphasize thoughtful patient and family education regarding therapeutic goals and their responsibility in helping to make the therapy successful.

Original languageEnglish (US)
Pages (from-to)228-233
Number of pages6
JournalSeminars in Pain Medicine
Issue number4
StatePublished - 2003
Externally publishedYes


  • Analgesia
  • Drug delivery systems
  • Intrathecal
  • Pain
  • Spasticity

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine


Dive into the research topics of 'Intrathecal drug therapy: General considerations'. Together they form a unique fingerprint.

Cite this