Investigation of a sensing approach based on a rapid reduction of azide to selectively measure bioavailability of H2S

Gunwoo Kim, Eunju Jang, Alexis M. Page, Ting Ding, Kimberly A. Carlson, Haishi Cao

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

A new reaction-based sensor (AHS) was synthesized for quantitative detection of H2S. AHS showed a high selectivity and sensitivity toward H2S over other thio-containing molecules, or reducing reagents with high abundance in living cells. In the presence of H2S, significant fluorescence enhancement (17-fold) was observed due to the reduction of the azide on AHS. The absorption (362 nm) and fluorescence emission (557 nm) of reduced AHS showed a highly linear correlation to H2S level, which were used to measure concentration of H2S in the range of 0-100 μM.

Original languageEnglish (US)
Pages (from-to)95920-95924
Number of pages5
JournalRSC Advances
Volume6
Issue number98
DOIs
StatePublished - 2016

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)

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