Investigation of a Sensing Strategy Based on a Nucleophilic Addition Reaction for Quantitative Detection of Bisulfite (HSO3)

Keith R. Everitt, Hannah C. Schmitz, Amanda Macke, Jinqing Shan, Eunju Jang, Brandon E. Luedtke, Kimberly A. Carlson, Haishi Cao

Research output: Contribution to journalArticle

Abstract

A reaction-based sensor (NAS-1) showed a high affinity and sensitivity to HSO3- via a nucleophilic addition reaction in the aqueous media, giving dual signals from absorption and emission spectra. NAS-1 was successfully applied in RK13 epithelial cells to detect HSO3- in a cellular environment.

Original languageEnglish (US)
Pages (from-to)977-983
Number of pages7
JournalJournal of Fluorescence
Volume30
Issue number5
DOIs
StatePublished - Sep 1 2020

Keywords

  • 1,8-naphthalimide
  • Bisulfite
  • Sensor

ASJC Scopus subject areas

  • Biochemistry
  • Clinical Psychology
  • Social Sciences (miscellaneous)
  • Sociology and Political Science
  • Spectroscopy
  • Clinical Biochemistry
  • Law

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