Is Isolated Systolic Hypertension Worse Than Combined Systolic/Diastolic Hypertension?

Yonggang Ma, Andriy Yabluchanskiy, Merry L. Lindsey, Robert J. Chilton

Research output: Contribution to journalEditorialpeer-review

4 Scopus citations


New developments in cardiovascular translational sciences have significantly advanced our understanding of the endovascular biology of blood pressure. Reductions in vascular elasticity and vessel compliance of conduit arteries are key components of both ISH and SDH. Vascular changes from the matrix metalloproteinase family of enzymes are involved in arterial wall remodeling and vascular stiffness. This new translational information helps further our understanding of both ISH and SDH.

Original languageEnglish (US)
Pages (from-to)808-809
Number of pages2
JournalJournal of Clinical Hypertension
Issue number11
StatePublished - Nov 2012
Externally publishedYes

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Cardiology and Cardiovascular Medicine


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