Lack of benefit with combination therapy for clostridium difficile infection

Jessica C. Njoku; Trevor C. Van Schooneveld; Mark E. Rupp; Keith M. Olsen; Fang Qiu; Jane L. Meza; Elizabeth D. Hermsen

doi:10.1017/ice.2016.320

Lack of benefit with combination therapy for clostridium difficile infection

Jessica C. Njoku, Trevor C. Van Schooneveld, Mark E. Rupp, Keith M. Olsen, Fang Qiu, Jane L. Meza, Elizabeth D. Hermsen

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Limited data exist regarding combination therapy for Clostridium difficile infection (CDI). After adjusting for confounders in a cohort of patients with CDI and≥1 year old, combination therapy was not associated with significant differences in clinical outcomes, but it was associated with prolonged duration of therapy (1.22 days; 95% confidence interval, 1.03-1.44 days; P=.02).

Original language	English (US)
Pages (from-to)	602-605
Number of pages	4
Journal	Infection Control and Hospital Epidemiology
Volume	38
Issue number	5
DOIs	https://doi.org/10.1017/ice.2016.320
State	Published - May 1 2017

ASJC Scopus subject areas

Epidemiology
Microbiology (medical)
Infectious Diseases

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10.1017/ice.2016.320

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abstract = "Limited data exist regarding combination therapy for Clostridium difficile infection (CDI). After adjusting for confounders in a cohort of patients with CDI and≥1 year old, combination therapy was not associated with significant differences in clinical outcomes, but it was associated with prolonged duration of therapy (1.22 days; 95% confidence interval, 1.03-1.44 days; P=.02).",

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AU - Qiu, Fang

AU - Meza, Jane L.

AU - Hermsen, Elizabeth D.

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AB - Limited data exist regarding combination therapy for Clostridium difficile infection (CDI). After adjusting for confounders in a cohort of patients with CDI and≥1 year old, combination therapy was not associated with significant differences in clinical outcomes, but it was associated with prolonged duration of therapy (1.22 days; 95% confidence interval, 1.03-1.44 days; P=.02).

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Lack of benefit with combination therapy for clostridium difficile infection

Abstract

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