Laminin and collagen IV enhanced casein synthesis in bovine mammary epithelial cells

T. Yano, H. Aso, K. Sakamoto, Y. Kobayashi, A. Hagino, K. Katoh, Y. Obara

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

In the bovine mammary gland, extracellular matrix proteins such as collagen I and IV and laminin coexist around the alveoli during lactation. In contrast, connexin, a gap junction protein, was scarce in lactating mammary epithelial cells. In addition, collagen IV and laminin were shown to be involved in alpha-casein synthesis and secretion in the bovine mammary epithelial cells. The connexin proteins, which were detected during the non-pregnant and dry periods, were scarce at peak lactation. It was shown that extracellular matrix proteins are important for the stimulation of casein synthesis, but this was accompanied by a suppression of connexin expression.

Original languageEnglish (US)
Pages (from-to)579-582
Number of pages4
JournalJournal of Animal and Feed Sciences
Volume13
Issue numberSUPPL. 1
DOIs
Publication statusPublished - Jan 1 2004

    Fingerprint

Keywords

  • Bovine
  • Casein synthesis
  • Collagen IV
  • Connexin
  • Extracellular matrix
  • Laminin

ASJC Scopus subject areas

  • Food Science
  • Animal Science and Zoology

Cite this

Yano, T., Aso, H., Sakamoto, K., Kobayashi, Y., Hagino, A., Katoh, K., & Obara, Y. (2004). Laminin and collagen IV enhanced casein synthesis in bovine mammary epithelial cells. Journal of Animal and Feed Sciences, 13(SUPPL. 1), 579-582. https://doi.org/10.22358/jafs/74043/2004