Large-cell anaplastic lymphoma-specific translocation in Hodgkin's disease

James R. Downing; Marc Ladanyi; Mark Raffeld; Lawrence M. Weiss; Stephan W. Morris; Sibrand Poppema; Daniel R. Lucey; Gene M. Shearer; Hartmut Merz; Karin Orscheschek; Brigitte Schlegelberger; Alfred C. Feller; Wing C. Chan; Goran Elmberger; Maria D. Lozano; Warren Sanger; Dennis D. Weisenburger

doi:10.1016/S0140-6736(95)90030-6

Large-cell anaplastic lymphoma-specific translocation in Hodgkin's disease

James R. Downing, Marc Ladanyi, Mark Raffeld, Lawrence M. Weiss, Stephan W. Morris, Sibrand Poppema, Daniel R. Lucey, Gene M. Shearer, Hartmut Merz, Karin Orscheschek, Brigitte Schlegelberger, Alfred C. Feller, Wing C. Chan, Goran Elmberger, Maria D. Lozano, Warren Sanger, Dennis D. Weisenburger

Cytogenetics

Research output: Contribution to journal › Letter › peer-review

14 Scopus citations

Original language	English (US)
Pages (from-to)	918-921
Number of pages	4
Journal	The Lancet
Volume	345
Issue number	8954
DOIs	https://doi.org/10.1016/S0140-6736(95)90030-6
State	Published - Apr 8 1995

ASJC Scopus subject areas

Medicine(all)

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Downing, J. R., Ladanyi, M., Raffeld, M., Weiss, L. M., Morris, S. W., Poppema, S., Lucey, D. R., Shearer, G. M., Merz, H., Orscheschek, K., Schlegelberger, B., Feller, A. C., Chan, W. C., Elmberger, G., Lozano, M. D., Sanger, W., & Weisenburger, D. D. (1995). Large-cell anaplastic lymphoma-specific translocation in Hodgkin's disease. The Lancet, 345(8954), 918-921. https://doi.org/10.1016/S0140-6736(95)90030-6

Downing, JR, Ladanyi, M, Raffeld, M, Weiss, LM, Morris, SW, Poppema, S, Lucey, DR, Shearer, GM, Merz, H, Orscheschek, K, Schlegelberger, B, Feller, AC, Chan, WC, Elmberger, G, Lozano, MD, Sanger, W & Weisenburger, DD 1995, 'Large-cell anaplastic lymphoma-specific translocation in Hodgkin's disease', The Lancet, vol. 345, no. 8954, pp. 918-921. https://doi.org/10.1016/S0140-6736(95)90030-6

@article{f28eb5235ae943ef98a7642b28742083,

title = "Large-cell anaplastic lymphoma-specific translocation in Hodgkin's disease",

author = "Downing, {James R.} and Marc Ladanyi and Mark Raffeld and Weiss, {Lawrence M.} and Morris, {Stephan W.} and Sibrand Poppema and Lucey, {Daniel R.} and Shearer, {Gene M.} and Hartmut Merz and Karin Orscheschek and Brigitte Schlegelberger and Feller, {Alfred C.} and Chan, {Wing C.} and Goran Elmberger and Lozano, {Maria D.} and Warren Sanger and Weisenburger, {Dennis D.}",

note = "Funding Information: efficient amplification of the NPM/ALK fusion message. Another possibility is that there are fundamental differences between the patient populations. Either the diagnostic criteria for Hodgkin{\textquoteright}s disease differ between the studies or there is a fundamental difference between Hodgkin{\textquoteright}s disease in Europe and North America. Whatever the ultimate reasons for the differences, results suggest that t(2;5) is rarely if ever detected in cases of Hodgkin{\textquoteright}s disease, and, furthermore, support the notion that Hodgkin{\textquoteright}s disease and t(2;5)-containing large-cell lymphoma distinct clinicopathological entities. This work was supported in part by NIH grants CA-01429 (JRD)j CA-50341 (LMW), Cancer Center Core Grant CA-21765, American Cancer Society Clinical Oncology Career Development Award 93-38 (ML), and by the American Lebanese Syrian Associated Charities of St Jude Children{\textquoteright}s Research Hospital.",

year = "1995",

month = apr,

day = "8",

doi = "10.1016/S0140-6736(95)90030-6",

language = "English (US)",

volume = "345",

pages = "918--921",

journal = "The Lancet",

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TY - JOUR

T1 - Large-cell anaplastic lymphoma-specific translocation in Hodgkin's disease

AU - Downing, James R.

AU - Ladanyi, Marc

AU - Raffeld, Mark

AU - Weiss, Lawrence M.

AU - Morris, Stephan W.

AU - Poppema, Sibrand

AU - Lucey, Daniel R.

AU - Shearer, Gene M.

AU - Merz, Hartmut

AU - Orscheschek, Karin

AU - Schlegelberger, Brigitte

AU - Feller, Alfred C.

AU - Chan, Wing C.

AU - Elmberger, Goran

AU - Lozano, Maria D.

AU - Sanger, Warren

AU - Weisenburger, Dennis D.

N1 - Funding Information: efficient amplification of the NPM/ALK fusion message. Another possibility is that there are fundamental differences between the patient populations. Either the diagnostic criteria for Hodgkin’s disease differ between the studies or there is a fundamental difference between Hodgkin’s disease in Europe and North America. Whatever the ultimate reasons for the differences, results suggest that t(2;5) is rarely if ever detected in cases of Hodgkin’s disease, and, furthermore, support the notion that Hodgkin’s disease and t(2;5)-containing large-cell lymphoma distinct clinicopathological entities. This work was supported in part by NIH grants CA-01429 (JRD)j CA-50341 (LMW), Cancer Center Core Grant CA-21765, American Cancer Society Clinical Oncology Career Development Award 93-38 (ML), and by the American Lebanese Syrian Associated Charities of St Jude Children’s Research Hospital.

PY - 1995/4/8

Y1 - 1995/4/8

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U2 - 10.1016/S0140-6736(95)90030-6

DO - 10.1016/S0140-6736(95)90030-6

M3 - Letter

C2 - 7755790

AN - SCOPUS:0028914823

SN - 0140-6736

VL - 345

SP - 918

EP - 921

JO - The Lancet

JF - The Lancet

IS - 8954

ER -

Large-cell anaplastic lymphoma-specific translocation in Hodgkin's disease

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