Abstract
Objective: To examine the short‐term cognitive and behavioral effects of L‐deprenyl in persons with mild dementia of the Alzheimer type (DAT) over a 2‐month period. Design: A 15‐month randomized, double‐blind, placebo‐controlled trial using a parallel‐group design. This report deals with the first 2 months of the trial. Participants: 39 subjects with mild DAT (CDR 1) selected using NINCDS‐ADRDA criteria. Measures: A battery of neuropsychological tests and clinical rating scales. Results: The placebo and L‐deprenyl subjects were similar at baseline on the clinical and neuropsychological tests. There was no evidence of a L‐deprenyl effect on any clinical or neuropsychological measures after 2 months. Conclusion: L‐deprenyl did not have a measurable impact on behavior or cognitive function over a 2‐month period in this group of subjects with mild DAT. 1993 The American Geriatrics Society
Original language | English (US) |
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Pages (from-to) | 367-370 |
Number of pages | 4 |
Journal | Journal of the American Geriatrics Society |
Volume | 41 |
Issue number | 4 |
DOIs | |
State | Published - Apr 1993 |
ASJC Scopus subject areas
- Geriatrics and Gerontology