Leiomyosarcoma of the Nasal Cavity and Paranasal Sinuses: A Case Report and Comprehensive Review of the Literature

Sumita S. Sam, Brian Stewart, Elham Nasri, Marino E. Leon, Ernesto Martinez Duarte

Research output: Contribution to journalReview articlepeer-review

Abstract

Sinonasal leiomyosarcoma (LMS) is a rare and aggressive mesenchymal tumor with smooth muscle differentiation. The sinonasal tract is an unusual primary site for LMS, as scant smooth muscle exists in this location, with only 75 cases reported in the English literature including the case presented herein. Sinonasal LMS is considered an aggressive head and neck tumor with significant potential for recurrence and metastasis. Since recurrence is high and the potential for late metastasis exists, lifelong follow-up in these patients would be beneficial, especially among those with previous history of RB.

Original languageEnglish (US)
JournalHead and Neck Pathology
DOIs
StateAccepted/In press - 2022
Externally publishedYes

Keywords

  • Leiomyosarcoma
  • Nasal cavity
  • Sinonasal
  • Sinus

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Otorhinolaryngology
  • Oncology

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