Leiomyosarcoma of the Nasal Cavity and Paranasal Sinuses: A Case Report and Comprehensive Review of the Literature

Sumita S. Sam; Brian Stewart; Elham Nasri; Marino E. Leon; Ernesto Martinez Duarte

doi:10.1007/s12105-022-01427-8

Leiomyosarcoma of the Nasal Cavity and Paranasal Sinuses: A Case Report and Comprehensive Review of the Literature

Sumita S. Sam, Brian Stewart, Elham Nasri, Marino E. Leon, Ernesto Martinez Duarte

Research output: Contribution to journal › Review article › peer-review

Abstract

Sinonasal leiomyosarcoma (LMS) is a rare and aggressive mesenchymal tumor with smooth muscle differentiation. The sinonasal tract is an unusual primary site for LMS, as scant smooth muscle exists in this location, with only 75 cases reported in the English literature including the case presented herein. Sinonasal LMS is considered an aggressive head and neck tumor with significant potential for recurrence and metastasis. Since recurrence is high and the potential for late metastasis exists, lifelong follow-up in these patients would be beneficial, especially among those with previous history of RB.

Original language	English (US)
Journal	Head and Neck Pathology
DOIs	https://doi.org/10.1007/s12105-022-01427-8
State	Accepted/In press - 2022
Externally published	Yes

Keywords

Leiomyosarcoma
Nasal cavity
Sinonasal
Sinus

ASJC Scopus subject areas

Pathology and Forensic Medicine
Otorhinolaryngology
Oncology

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10.1007/s12105-022-01427-8

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title = "Leiomyosarcoma of the Nasal Cavity and Paranasal Sinuses: A Case Report and Comprehensive Review of the Literature",

abstract = "Sinonasal leiomyosarcoma (LMS) is a rare and aggressive mesenchymal tumor with smooth muscle differentiation. The sinonasal tract is an unusual primary site for LMS, as scant smooth muscle exists in this location, with only 75 cases reported in the English literature including the case presented herein. Sinonasal LMS is considered an aggressive head and neck tumor with significant potential for recurrence and metastasis. Since recurrence is high and the potential for late metastasis exists, lifelong follow-up in these patients would be beneficial, especially among those with previous history of RB.",

keywords = "Leiomyosarcoma, Nasal cavity, Sinonasal, Sinus",

author = "Sam, {Sumita S.} and Brian Stewart and Elham Nasri and Leon, {Marino E.} and {Martinez Duarte}, Ernesto",

note = "Publisher Copyright: {\textcopyright} 2022, The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature.",

year = "2022",

doi = "10.1007/s12105-022-01427-8",

language = "English (US)",

journal = "Head and Neck Pathology",

issn = "1936-055X",

publisher = "Humana Press",

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TY - JOUR

T1 - Leiomyosarcoma of the Nasal Cavity and Paranasal Sinuses

T2 - A Case Report and Comprehensive Review of the Literature

AU - Sam, Sumita S.

AU - Stewart, Brian

AU - Nasri, Elham

AU - Leon, Marino E.

AU - Martinez Duarte, Ernesto

PY - 2022

Y1 - 2022

N2 - Sinonasal leiomyosarcoma (LMS) is a rare and aggressive mesenchymal tumor with smooth muscle differentiation. The sinonasal tract is an unusual primary site for LMS, as scant smooth muscle exists in this location, with only 75 cases reported in the English literature including the case presented herein. Sinonasal LMS is considered an aggressive head and neck tumor with significant potential for recurrence and metastasis. Since recurrence is high and the potential for late metastasis exists, lifelong follow-up in these patients would be beneficial, especially among those with previous history of RB.

AB - Sinonasal leiomyosarcoma (LMS) is a rare and aggressive mesenchymal tumor with smooth muscle differentiation. The sinonasal tract is an unusual primary site for LMS, as scant smooth muscle exists in this location, with only 75 cases reported in the English literature including the case presented herein. Sinonasal LMS is considered an aggressive head and neck tumor with significant potential for recurrence and metastasis. Since recurrence is high and the potential for late metastasis exists, lifelong follow-up in these patients would be beneficial, especially among those with previous history of RB.

KW - Leiomyosarcoma

KW - Nasal cavity

KW - Sinonasal

KW - Sinus

UR - http://www.scopus.com/inward/record.url?scp=85124754256&partnerID=8YFLogxK

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U2 - 10.1007/s12105-022-01427-8

DO - 10.1007/s12105-022-01427-8

M3 - Review article

C2 - 35157212

AN - SCOPUS:85124754256

JO - Head and Neck Pathology

JF - Head and Neck Pathology

SN - 1936-055X

ER -

Leiomyosarcoma of the Nasal Cavity and Paranasal Sinuses: A Case Report and Comprehensive Review of the Literature

Abstract

Keywords

ASJC Scopus subject areas

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