Linear, redox modified DNA probes as electrochemical DNA sensors

Francesco Ricci, Rebecca Y. Lai, Kevin W. Plaxco

Research output: Contribution to journalArticlepeer-review

107 Scopus citations


We show here that hybridization-linked changes in the dynamics of a redox-modified, electrode-bound linear (as opposed to stem-loop) probe DNA produce large changes in Faradaic current, allowing for the ready detection of target oligonucleotides.

Original languageEnglish (US)
Pages (from-to)3768-3770
Number of pages3
JournalChemical Communications
Issue number36
StatePublished - 2007
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • General Chemistry
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry


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