Linkage of usher syndrome type I gene (USH1B) to the long arm of chromosome 11

W. J. Kimberling; C. G. Möller; S. Davenport; I. A. Priluck; P. H. Beighton; J. Greenberg; W. Reardon; M. D. Weston; J. B. Kenyon; J. A. Grunkemeyer; S. Pieke Dahl; L. D. Overbeck; D. J. Blackwood; A. M. Brower; D. M. Hoover; P. Rowland; R. J.H. Smith

doi:10.1016/S0888-7543(05)80121-1

Linkage of usher syndrome type I gene (USH1B) to the long arm of chromosome 11

W. J. Kimberling, C. G. Möller, S. Davenport, I. A. Priluck, P. H. Beighton, J. Greenberg, W. Reardon, M. D. Weston, J. B. Kenyon, J. A. Grunkemeyer, S. Pieke Dahl, L. D. Overbeck, D. J. Blackwood, A. M. Brower, D. M. Hoover, P. Rowland, R. J.H. Smith

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Abstract

Usher syndrome is the most commonly recognized cause of combined visual and hearing loss in technologically developed countries. There are several different types and all are inherited in an autosomal recessive manner. There may be as many as five different genes responsible for at least two closely related phenotypes. The nature of the gene defects is unknown, and positional cloning strategies are being employed to identify the genes. This is a report of the localization of one gene for Usher syndrome type I to chromosome 11q, probably distal to marker D11S527. Another USH1 gene had been previously localized to chromosome 14q, and this second localization establishes the existence of a new and independent locus for Usher syndrome.

Original language	English (US)
Pages (from-to)	988-994
Number of pages	7
Journal	Genomics
Volume	14
Issue number	4
DOIs	https://doi.org/10.1016/S0888-7543(05)80121-1
State	Published - Dec 1992

ASJC Scopus subject areas

Genetics

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Kimberling, W. J., Möller, C. G., Davenport, S., Priluck, I. A., Beighton, P. H., Greenberg, J., Reardon, W., Weston, M. D., Kenyon, J. B., Grunkemeyer, J. A., Pieke Dahl, S., Overbeck, L. D., Blackwood, D. J., Brower, A. M., Hoover, D. M., Rowland, P., & Smith, R. J. H. (1992). Linkage of usher syndrome type I gene (USH1B) to the long arm of chromosome 11. Genomics, 14(4), 988-994. https://doi.org/10.1016/S0888-7543(05)80121-1

Kimberling, WJ, Möller, CG, Davenport, S, Priluck, IA, Beighton, PH, Greenberg, J, Reardon, W, Weston, MD, Kenyon, JB, Grunkemeyer, JA, Pieke Dahl, S, Overbeck, LD, Blackwood, DJ, Brower, AM, Hoover, DM, Rowland, P & Smith, RJH 1992, 'Linkage of usher syndrome type I gene (USH1B) to the long arm of chromosome 11', Genomics, vol. 14, no. 4, pp. 988-994. https://doi.org/10.1016/S0888-7543(05)80121-1

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title = "Linkage of usher syndrome type I gene (USH1B) to the long arm of chromosome 11",

abstract = "Usher syndrome is the most commonly recognized cause of combined visual and hearing loss in technologically developed countries. There are several different types and all are inherited in an autosomal recessive manner. There may be as many as five different genes responsible for at least two closely related phenotypes. The nature of the gene defects is unknown, and positional cloning strategies are being employed to identify the genes. This is a report of the localization of one gene for Usher syndrome type I to chromosome 11q, probably distal to marker D11S527. Another USH1 gene had been previously localized to chromosome 14q, and this second localization establishes the existence of a new and independent locus for Usher syndrome.",

author = "Kimberling, {W. J.} and M{\"o}ller, {C. G.} and S. Davenport and Priluck, {I. A.} and Beighton, {P. H.} and J. Greenberg and W. Reardon and Weston, {M. D.} and Kenyon, {J. B.} and Grunkemeyer, {J. A.} and {Pieke Dahl}, S. and Overbeck, {L. D.} and Blackwood, {D. J.} and Brower, {A. M.} and Hoover, {D. M.} and P. Rowland and Smith, {R. J.H.}",

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doi = "10.1016/S0888-7543(05)80121-1",

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AU - Kimberling, W. J.

AU - Möller, C. G.

AU - Davenport, S.

AU - Priluck, I. A.

AU - Beighton, P. H.

AU - Greenberg, J.

AU - Reardon, W.

AU - Weston, M. D.

AU - Kenyon, J. B.

AU - Grunkemeyer, J. A.

AU - Pieke Dahl, S.

AU - Overbeck, L. D.

AU - Blackwood, D. J.

AU - Brower, A. M.

AU - Hoover, D. M.

AU - Rowland, P.

AU - Smith, R. J.H.

PY - 1992/12

Y1 - 1992/12

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AB - Usher syndrome is the most commonly recognized cause of combined visual and hearing loss in technologically developed countries. There are several different types and all are inherited in an autosomal recessive manner. There may be as many as five different genes responsible for at least two closely related phenotypes. The nature of the gene defects is unknown, and positional cloning strategies are being employed to identify the genes. This is a report of the localization of one gene for Usher syndrome type I to chromosome 11q, probably distal to marker D11S527. Another USH1 gene had been previously localized to chromosome 14q, and this second localization establishes the existence of a new and independent locus for Usher syndrome.

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Linkage of usher syndrome type I gene (USH1B) to the long arm of chromosome 11

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