Liver transplant for congenital factor VII deficiency

Research output: Contribution to journalArticlepeer-review

4 Scopus citations


Congenital factor VII (FVII) deficiency is a rare, autosomal recessive bleeding disorder with a spectrum of phenotypes ranging from asymptomatic to life-threatening intra-cranial hemorrhage (ICH). Orthotopic liver transplantation has been described for definitive treatment in a few patients with severe manifestations. We report a patient with congenital FVII deficiency and recurrent ICH, despite twice-weekly prophylaxis with recombinant activated FVII. At 17 months of age, he underwent an orthotopic liver transplant. He is now 1-year post-transplant, on maintenance immunosuppression with no hemorrhage or other complications.

Original languageEnglish (US)
Pages (from-to)1886-1887
Number of pages2
JournalPediatric Blood and Cancer
Issue number10
StatePublished - Oct 2014


  • Factor VII deficiency
  • Liver transplant

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Hematology
  • Oncology


Dive into the research topics of 'Liver transplant for congenital factor VII deficiency'. Together they form a unique fingerprint.

Cite this