Localization of Acid Phosphatase Activity in Giardia lamblia and Giardia muris Trophozoites

DENNIS E. FEELY, JOHN K. DYER

Research output: Contribution to journalArticle

48 Scopus citations

Abstract

Numerous membrane‐bounded vacuoles are found adjacent to the plasma membrane of the pathogenic protozoan Giardia lamblia. The function of these vacuoles has been discussed by several authors. Approximately 100–400 nm in diameter with a core of low electron density, they have been suggested to be mitochondria, mucocysts, lysosomes, and endocytotic vacuoles. Enzyme cytochemical localization for acid phosphatase activity using cerium as a capturing agent demonstrates reaction product in these vacuoles as well as in the endoplasmic reticulum and nuclear envelope cisternae. The distribution of reaction product suggests the vacuoles are lysosome‐like; however, their function and development remain in question.

Original languageEnglish (US)
Pages (from-to)80-83
Number of pages4
JournalThe Journal of protozoology
Volume34
Issue number1
DOIs
StatePublished - Feb 1987

ASJC Scopus subject areas

  • Parasitology

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