Abstract
Significant linkage was found between spherocytosis and a translocation involving the short arms of chromosomes 8 and 12. The gene for spherocytosis, therefore, is likely either very close to the centromere of chromosome 8 or on 12p. The unusually high frequency of spontaneous abortion in this family was probably due to this translocation and was unrelated to the spherocytosis.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 586-594 |
| Number of pages | 9 |
| Journal | American Journal of Human Genetics |
| Volume | 27 |
| Issue number | 5 |
| State | Published - 1975 |
| Externally published | Yes |
ASJC Scopus subject areas
- Genetics
- Genetics(clinical)
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Kimberling, W. J., Fulbeck, T., Dixon, L., & Lubs, H. A. (1975). Localization of spherocytosis to chromosome 8 or 12 and report of a family with spherocytosis and a reciprocal translocation. American Journal of Human Genetics, 27(5), 586-594.