Abstract
Significant linkage was found between spherocytosis and a translocation involving the short arms of chromosomes 8 and 12. The gene for spherocytosis, therefore, is likely either very close to the centromere of chromosome 8 or on 12p. The unusually high frequency of spontaneous abortion in this family was probably due to this translocation and was unrelated to the spherocytosis.
Original language | English (US) |
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Pages (from-to) | 586-594 |
Number of pages | 9 |
Journal | American Journal of Human Genetics |
Volume | 27 |
Issue number | 5 |
State | Published - 1975 |
Externally published | Yes |
ASJC Scopus subject areas
- Genetics
- Genetics(clinical)