Localization of spherocytosis to chromosome 8 or 12 and report of a family with spherocytosis and a reciprocal translocation

W. J. Kimberling, T. Fulbeck, L. Dixon, H. A. Lubs

Research output: Contribution to journalArticlepeer-review

27 Scopus citations

Abstract

Significant linkage was found between spherocytosis and a translocation involving the short arms of chromosomes 8 and 12. The gene for spherocytosis, therefore, is likely either very close to the centromere of chromosome 8 or on 12p. The unusually high frequency of spontaneous abortion in this family was probably due to this translocation and was unrelated to the spherocytosis.

Original languageEnglish (US)
Pages (from-to)586-594
Number of pages9
JournalAmerican Journal of Human Genetics
Volume27
Issue number5
StatePublished - 1975

ASJC Scopus subject areas

  • Genetics
  • Genetics(clinical)

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