Long noncoding RNAs in immune response, viral infection, and opioid use

Rong Ma, Palsamy Periyasamy, Raghubendra Singh Dagur, Susmita Sil, Zhongbin Wang, Shilpa Buch, Guoku Hu

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Long noncoding RNAs (lncRNAs) have been recognized as key regulators of immune responses and host–virus interactions. Dysregulation of lncRNAs during viral infections and under various inflammatory conditions as well as the functions of these lncRNAs in the resolution of immune responses and viral infections has been extensively studied. Drug abusers, such as opioid abusers, are at high risk for and have a high rate of viral infections, including HIV-1. Emerging evidence suggests that lncRNAs play key roles in opioid use disorders (OUDs). This chapter focuses on the functions of dysregulated lncRNAs involved in the inflammatory and immune responses and viral infections, including human immunodeficiency virus, hepatitis B virus, hepatitis C virus, influenza A virus infections, and OUDs.

Original languageEnglish (US)
Title of host publicationHIV-Associated Neurocognitive Disorders
PublisherElsevier
Pages487-502
Number of pages16
ISBN (Electronic)9780323997447
ISBN (Print)9780323997454
DOIs
StatePublished - Jan 1 2024

Keywords

  • Antiretroviral therapy
  • Drug abuse
  • Human immunodeficiency virus
  • Long noncoding RNAs
  • Opioid use disorders

ASJC Scopus subject areas

  • General Psychology

Fingerprint

Dive into the research topics of 'Long noncoding RNAs in immune response, viral infection, and opioid use'. Together they form a unique fingerprint.

Cite this