Abstract
Long noncoding RNAs (lncRNAs) have been recognized as key regulators of immune responses and host–virus interactions. Dysregulation of lncRNAs during viral infections and under various inflammatory conditions as well as the functions of these lncRNAs in the resolution of immune responses and viral infections has been extensively studied. Drug abusers, such as opioid abusers, are at high risk for and have a high rate of viral infections, including HIV-1. Emerging evidence suggests that lncRNAs play key roles in opioid use disorders (OUDs). This chapter focuses on the functions of dysregulated lncRNAs involved in the inflammatory and immune responses and viral infections, including human immunodeficiency virus, hepatitis B virus, hepatitis C virus, influenza A virus infections, and OUDs.
Original language | English (US) |
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Title of host publication | HIV-Associated Neurocognitive Disorders |
Publisher | Elsevier |
Pages | 487-502 |
Number of pages | 16 |
ISBN (Electronic) | 9780323997447 |
ISBN (Print) | 9780323997454 |
DOIs | |
State | Published - Jan 1 2024 |
Keywords
- Antiretroviral therapy
- Drug abuse
- Human immunodeficiency virus
- Long noncoding RNAs
- Opioid use disorders
ASJC Scopus subject areas
- General Psychology