Lorenzo's Oil – Hope and Disappointment

Research output: Contribution to journalEditorial

27 Scopus citations

Abstract

The rational development of therapy for a disease depends critically on knowledge about its pathogenesis. In the absence of such insight, physicians are vulnerable to the prevailing winds of opinion and practice, each liable to shift from one moment to another. Even when a therapeutic approach seems logical, it must still be proved effective – not by anecdotal reports, surrogate responses, or public opinion, but by the scientific method and the performance of clinical trials. Such is the case for dietary therapy of adrenoleukodystrophy, a rare and devastating neurodegenerative disease. A recent popular film, Lorenzo's Oil, prematurely implied that dietary…

Original languageEnglish (US)
Pages (from-to)801-802
Number of pages2
JournalNew England Journal of Medicine
Volume329
Issue number11
DOIs
StatePublished - Sep 9 1993

ASJC Scopus subject areas

  • Medicine(all)

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