Lowering threshold energy for femtosecond laser pulse photodisruption through turbid media using adaptive optics

A. Hansen, Tammo Ripken, Ronald R. Krueger, Holger Lubatschowski

Research output: Chapter in Book/Report/Conference proceedingConference contribution


Focussed femtosecond laser pulses are applied in ophthalmic tissues to create an optical breakdown and therefore a tissue dissection through photodisruption. The threshold irradiance for the optical breakdown depends on the photon density in the focal volume which can be influenced by the pulse energy, the size of the irradiated area (focus), and the irradiation time. For an application in the posterior eye segment the aberrations of the anterior eye elements cause a distortion of the wavefront and therefore an increased focal volume which reduces the photon density and thus raises the required energy for surpassing the threshold irradiance. The influence of adaptive optics on lowering the pulse energy required for photodisruption by refining a distorted focus was investigated. A reduction of the threshold energy can be shown when using adaptive optics. The spatial confinement with adaptive optics furthermore raises the irradiance at constant pulse energy. The lowered threshold energy allows for tissue dissection with reduced peripheral damage. This offers the possibility for moving femtosecond laser surgery from corneal or lental applications in the anterior eye to vitreal or retinal applications in the posterior eye.

Original languageEnglish (US)
Title of host publicationOphthalmic Technologies XXI
StatePublished - 2011
Externally publishedYes
EventOphthalmic Technologies XXI - San Francisco, CA, United States
Duration: Jan 22 2011Jan 24 2011

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN (Print)1605-7422


ConferenceOphthalmic Technologies XXI
Country/TerritoryUnited States
CitySan Francisco, CA


  • Adaptive optics
  • aberrations
  • femtosecond laser
  • laser beam shaping
  • laser surgery
  • ophthalmology
  • optical breakdown
  • photodisruption

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging


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