Abstract
Luminescent, cell-based assays capable of monitoring the aggregation potential of the disease-relevant proteins known as amylin (type 2 diabetes) and huntingtin (Huntington's disease) are presented. These sensitive platforms report on the influence of mutations as well as small molecules on protein solubility.
Original language | English (US) |
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Pages (from-to) | 2984-2987 |
Number of pages | 4 |
Journal | Molecular BioSystems |
Volume | 12 |
Issue number | 10 |
DOIs | |
State | Published - 2016 |
ASJC Scopus subject areas
- Biotechnology
- Molecular Biology