Lymphoma and Targeted Therapies

Sonali M. Smith, Julie M. Vose

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

With further understanding of the origin of lymphoma cellular components for the various subtypes, specific pathways and targets are being identified. Many of the recent clinical trials of lymphoma therapies include targeting of specific surface antigens or cellular pathways. Over the past couple of decades, first monoclonal antibodies were developed and more recently agents that focus on pathways in B or T lymphocytes, or the microenvironment that supports the lymphoma growth. This review will focus on a selected subset of targets based on promising clinical agents for the treatment of lymphoma.

Original languageEnglish (US)
Title of host publicationTargeted Therapy in Translational Cancer Research
PublisherWiley-Blackwell
Pages169-176
Number of pages8
ISBN (Electronic)9781118468678
ISBN (Print)9781118468579
DOIs
StatePublished - Oct 30 2015

Keywords

  • B-cell receptor pathway
  • Microenvironment
  • Monoclonal antibody
  • Non-Hodgkin's lymphoma

ASJC Scopus subject areas

  • Medicine(all)

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