Macrophages and the human immunodeficiency virus

Monte S. Meltzer, Donald R. Skillman, David L. Hoover, Brian D. Hanson, Jim A. Turpin, D. Chester Kalter, Howard E. Gendelman

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

Mononuclear phagocytes are major participants in human immunodeficiency virus (HIV) disease. These cells function as susceptible targets, persistent reservoirs for virus in tissue and key immunoregulatory elements that control the level of virus replication and the extent of disease. In this review, the second of the series, Monte Meltzer and colleagues review the distinct interactions between HIV and monocytes and between HIV and T cells. Understanding this dualism may more clearly define both the pathogenesis of HIV disease and strategies for therapeutic intervention.

Original languageEnglish (US)
Pages (from-to)217-223
Number of pages7
JournalTrends in Immunology
Volume11
Issue numberC
StatePublished - 1990

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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    Meltzer, M. S., Skillman, D. R., Hoover, D. L., Hanson, B. D., Turpin, J. A., Kalter, D. C., & Gendelman, H. E. (1990). Macrophages and the human immunodeficiency virus. Trends in Immunology, 11(C), 217-223.