Magnetic Nanoparticles in Cancer Therapy and Diagnosis

Ali Farzin, Seyed Alireza Etesami, Jacob Quint, Adnan Memic, Ali Tamayol

Research output: Contribution to journalReview articlepeer-review

291 Scopus citations


There is urgency for the development of nanomaterials that can meet emerging biomedical needs. Magnetic nanoparticles (MNPs) offer high magnetic moments and surface-area-to-volume ratios that make them attractive for hyperthermia therapy of cancer and targeted drug delivery. Additionally, they can function as contrast agents for magnetic resonance imaging (MRI) and can improve the sensitivity of biosensors and diagnostic tools. Recent advancements in nanotechnology have resulted in the realization of the next generation of MNPs suitable for these and other biomedical applications. This review discusses methods utilized for the fabrication and engineering of MNPs. Recent progress in the use of MNPs for hyperthermia therapy, controlling drug release, MRI, and biosensing is also critically reviewed. Finally, challenges in the field and potential opportunities for the use of MNPs toward improving their properties are discussed.

Original languageEnglish (US)
Article number1901058
JournalAdvanced Healthcare Materials
Issue number9
StatePublished - May 1 2020


  • cancer detection
  • cancer therapy
  • drug delivery
  • hyperthermia
  • magnetic nanoparticles

ASJC Scopus subject areas

  • Biomaterials
  • Biomedical Engineering
  • Pharmaceutical Science


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