@article{76fa4e6dd0ce4cdabb9ea0edf626d3d6,
title = "Maintenance of CTCF- and Transcription Factor-Mediated Interactions from the Gametes to the Early Mouse Embryo",
abstract = "Jung et al. show that sperm and oocyte promoters and enhancers contain ATAC-seq accessible sites suggesting the presence of Pol II, Foxa1, ERα, and AR. Accessibility in gametes persists in early embryos. Interactions mediated by CTCF in gametes are inherited from each parent and become the same in 8-cell embryos.",
keywords = "Foxa1, androgen, chromatin, development, enhancer, estrogen, fertilization, oocyte, sperm, transcription",
author = "Jung, {Yoon Hee} and Isaac Kremsky and Gold, {Hannah B.} and Rowley, {M. Jordan} and Kanchana Punyawai and Alyx Buonanotte and Xiaowen Lyu and Bixler, {Brianna J.} and Chan, {Anthony W.S.} and Corces, {Victor G.}",
note = "Funding Information: We would like to thank the Genomic Services Lab at the HudsonAlpha Institute for Biotechnology, especially Drs. Angela Jones and Braden Boone, for their help in performing Illumina sequencing of samples. This work was supported by US Public Health Service Award R01 ES027859 from the NIH (to V.G.C.). Rhesus macaque sperm samples were provided by the Transgenic Huntington{\textquoteright}s Disease Monkey Resource (THDMR; OD010930 ), sponsored by the Office of Research and Infrastructure Programs (ORIP) at the NIH . M.J.R. was supported by NIH Pathway to Independence Award NIGMS K99GM127671 . The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. Funding Information: We would like to thank the Genomic Services Lab at the HudsonAlpha Institute for Biotechnology, especially Drs. Angela Jones and Braden Boone, for their help in performing Illumina sequencing of samples. This work was supported by US Public Health Service Award R01 ES027859 from the NIH (to V.G.C.). Rhesus macaque sperm samples were provided by the Transgenic Huntington's Disease Monkey Resource (THDMR; OD010930), sponsored by the Office of Research and Infrastructure Programs (ORIP) at the NIH. M.J.R. was supported by NIH Pathway to Independence Award NIGMS K99GM127671. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. Y.H.J. planned and performed experiments, analyzed the data, and wrote the manuscript. I.K. analyzed the data and contributed to writing the manuscript. H.B.G. performed experiments and contributed to writing the manuscript. M.J.R. and B.J.B. analyzed the data. K.P. A.B. and X.L. performed experiments. A.W.S.C. planned experiments. VGC planned the experiments and contributed to writing the manuscript. The authors declare no competing interests. Publisher Copyright: {\textcopyright} 2019 Elsevier Inc.",
year = "2019",
month = jul,
day = "11",
doi = "10.1016/j.molcel.2019.04.014",
language = "English (US)",
volume = "75",
pages = "154--171.e5",
journal = "Molecular Cell",
issn = "1097-2765",
publisher = "Cell Press",
number = "1",
}