Making smart investment decisions in clinical research

Nick Bansback; Edward Keystone; James O'Dell; Ciaran S. Phibbs; Keri Hannagan; Mary Brophy; Aslam Anis

doi:10.1186/s13063-015-1123-1

Making smart investment decisions in clinical research

Nick Bansback, Edward Keystone, James O'Dell, Ciaran S. Phibbs, Keri Hannagan, Mary Brophy, Aslam Anis

Research output: Contribution to journal › Comment/debate › peer-review

2 Scopus citations

Abstract

A recent trial in rheumatoid arthritis found an inexpensive, but infrequently used, combination of therapies is neither inferior nor less safe than an expensive biologic drug. If the trial had been conducted over 10 years ago, arguably 100's of millions of dollars since spent on biologics could have been released to other, more effective treatments. Given the ever increasing number of trials proposed, this commentary uses the trial as an example to challenge payers and research funders to make smarter investments in clinical research to save potential future costs.

Original language	English (US)
Article number	590
Journal	Trials
Volume	16
Issue number	1
DOIs	https://doi.org/10.1186/s13063-015-1123-1
State	Published - Dec 29 2015

Keywords

Economics
Randomized trials
Rheumatoid arthritis

ASJC Scopus subject areas

Medicine (miscellaneous)
Pharmacology (medical)

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title = "Making smart investment decisions in clinical research",

abstract = "A recent trial in rheumatoid arthritis found an inexpensive, but infrequently used, combination of therapies is neither inferior nor less safe than an expensive biologic drug. If the trial had been conducted over 10 years ago, arguably 100's of millions of dollars since spent on biologics could have been released to other, more effective treatments. Given the ever increasing number of trials proposed, this commentary uses the trial as an example to challenge payers and research funders to make smarter investments in clinical research to save potential future costs.",

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AU - Bansback, Nick

AU - Keystone, Edward

AU - O'Dell, James

AU - Phibbs, Ciaran S.

AU - Hannagan, Keri

AU - Brophy, Mary

AU - Anis, Aslam

PY - 2015/12/29

Y1 - 2015/12/29

N2 - A recent trial in rheumatoid arthritis found an inexpensive, but infrequently used, combination of therapies is neither inferior nor less safe than an expensive biologic drug. If the trial had been conducted over 10 years ago, arguably 100's of millions of dollars since spent on biologics could have been released to other, more effective treatments. Given the ever increasing number of trials proposed, this commentary uses the trial as an example to challenge payers and research funders to make smarter investments in clinical research to save potential future costs.

AB - A recent trial in rheumatoid arthritis found an inexpensive, but infrequently used, combination of therapies is neither inferior nor less safe than an expensive biologic drug. If the trial had been conducted over 10 years ago, arguably 100's of millions of dollars since spent on biologics could have been released to other, more effective treatments. Given the ever increasing number of trials proposed, this commentary uses the trial as an example to challenge payers and research funders to make smarter investments in clinical research to save potential future costs.

KW - Economics

KW - Randomized trials

KW - Rheumatoid arthritis

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Making smart investment decisions in clinical research

Abstract

Keywords

ASJC Scopus subject areas

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