Management of Ventilator-Associated Pneumonia: Guidelines

Mark L. Metersky, Andre C. Kalil

Research output: Contribution to journalReview articlepeer-review

15 Scopus citations


Two recent major guidelines on diagnosis and treatment of ventilator-associated pneumonia (VAP) recommend consideration of local antibiotic resistance patterns and individual patient risks for resistant pathogens when formulating an initial empiric antibiotic regimen. One recommends against invasive diagnostic techniques with quantitative cultures to determine the cause of VAP; the other recommends either invasive or noninvasive techniques. Both guidelines recommend short-course therapy be used for most patients with VAP. Although neither guideline recommends use of procalcitonin as an adjunct to clinical judgment when diagnosing VAP, they differ with respect to use of serial procalcitonin to shorten the length of antibiotic treatment.

Original languageEnglish (US)
Pages (from-to)797-808
Number of pages12
JournalClinics in Chest Medicine
Issue number4
StatePublished - Dec 2018


  • Guideline
  • Hospital-acquired pneumonia
  • Nosocomial pneumonia
  • Ventilator-associated pneumonia

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine


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