Mechanical characterization of the layer-specific human aorta

Shijia Zhao, Linxia Gu, Shengmao Lin

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

In this work, three layers of human aorta, i.e. intima, media and adventitia, obtained from a 9 mm CryoValve® aortic valve allograft, were tested along both axial and circumferential directions. Preconditioning with a stretch ratio of 1.35 was used to mimic the physiological pulsatile loading conditions of the tissue. Results suggested that the stiffness along circumferential direction is generally larger than axial direction in each of the three layers. In all three layers, the media layer is the stiffest, and the adventitia layer is the softest regardless of testing directions. The anisotropic, nonlinear elastic mechanical behavior of each layer from the aortic valve allograft could help better understand the compliance mismatch between the allograft and native arterial tissue.

Original languageEnglish (US)
Title of host publicationASME 2012 International Mechanical Engineering Congress and Exposition, IMECE 2012
Pages269-270
Number of pages2
DOIs
StatePublished - 2012
EventASME 2012 International Mechanical Engineering Congress and Exposition, IMECE 2012 - Houston, TX, United States
Duration: Nov 9 2012Nov 15 2012

Publication series

NameASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE)
Volume2

Conference

ConferenceASME 2012 International Mechanical Engineering Congress and Exposition, IMECE 2012
CountryUnited States
CityHouston, TX
Period11/9/1211/15/12

ASJC Scopus subject areas

  • Mechanical Engineering

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