@article{d63b5436a0a4434caea6e0df8337f85b,
title = "Mechanisms of NOD-like receptor-associated inflammasome activation",
abstract = "A major function of a subfamily of NLR (nucleotide-binding domain, leucine-rich repeat containing, or NOD-like receptor) proteins is in inflammasome activation, which has been implicated in a multitude of disease models and human diseases. This work will highlight key progress in understanding the mechanisms that activate the best-studied NLRs (NLRP3, NLRC4, NAIP, and NLRP1) and in uncovering inflammasome NLRs.",
author = "Haitao Wen and Miao, {Edward A.} and Ting, {Jenny P.Y.}",
note = "Funding Information: This work was supported by National Institutes of Health grants R37-AI029564, U54-AI057157 (SERCEB), U19AI077437, U19AI067798, and CA156330 awarded to J.P.-Y.T., NIH grants AI097518 and AI057141 awarded to E.A.M., and NIH grant K01DK098307 awarded to H.W. H.W. is a recipient of Postdoctoral Fellowship of the American Heart Association (Mid-Atlantic Affiliate) and Postdoctoral Fellowship of Cancer Research Institute. We thank M. Moayeri for helpful discussions.",
year = "2013",
month = sep,
day = "19",
doi = "10.1016/j.immuni.2013.08.037",
language = "English (US)",
volume = "39",
pages = "432--441",
journal = "Immunity",
issn = "1074-7613",
publisher = "Cell Press",
number = "3",
}