Mechanistic details of glutathione biosynthesis revealed by crystal structures of Saccharomyces cerevisiae glutamate cysteine ligase

Medicine & Life Sciences

• Glutamate-Cysteine Ligase 100%
• Saccharomyces cerevisiae 64%
• Glutathione 63%
• Magnesium Chloride 62%
• Glutamic Acid 61%
• human GCLC protein 53%
• Enzymes 25%
• Sulfhydryl Compounds 25%
• Disulfides 24%
• Post Translational Protein Processing 24%
• Adenosine Diphosphate 23%
• Cysteine 22%
• Disease Progression 18%
• Adenosine Triphosphate 18%
• Oxidative Stress 17%
• Peptides 14%
• Mutation 13%

Chemical Compounds

• Glutathione 62%
• Cysteine 60%
• Biosynthesis 58%
• Crystal Structure 34%
• Detoxification 11%
• Cysteine Residue 10%
• ADP 10%
• Enzymatic Reaction 10%
• Oxidative Stress 9%
• Cofactor 9%
• Mutation 8%
• Enzyme Activity 8%
• Peptide 5%
• Modification 5%