Mechanomyographic Amplitude Is Sensitive to Load-Dependent Neuromuscular Adaptations in Response to Resistance Training

Nathaniel D.M. Jenkins, Amelia A. Miramonti, Ethan C. Hill, Cory M. Smith, Kristen C. Cochrane-Snyman, Terry J. Housh, Joel T. Cramer

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1 Scopus citations


Jenkins, NDM, Miramonti, AA, Hill, EC, Smith, CM, Cochrane-Snyman, KC, Housh, TJ, and Cramer, JT. Mechanomyographic amplitude is sensitive to load-dependent neuromuscular adaptations in response to resistance training. J Strength Cond Res 35(11): 3265-3269, 2021-We examined the sensitivity of the mechanomyographic amplitude (MMGRMS) and frequency (MMGMPF) vs.Torque relationships to load-dependent neuromuscular adaptations in response to 6 weeks of higher-vs. lower-load resistance training. Twenty-five men (age = 22.8 ± 4.6 years) were randomly assigned to either a high-(n = 13) or low-load (n = 12) training group and completed 6 weeks of leg extension resistance training at 80 or 30% 1RM. Before and after 3 and 6 weeks of training, mechanomyography signals were recorded during isometric contractions at target torques equal to 10-100% of the subjects' baseline maximal strength to quantify MMGRMSand MMGMPFvs.Torque relationships. MMGRMSdecreased from Baseline to weeks 3 and 6 in the high-load, but not low-load group, and was dependent on the muscle and intensity of contraction examined. Consequently, MMGRMSwas generally lower in the high-than low-load group at weeks 3 and 6, and these differences were most apparent in the vastus lateralis (VL) and rectus femoris muscles at higher contraction intensities. MMGMPFwas greater in the high-than low-load training group independent of time or muscle. The MMGRMSvs.Torque relationship was sensitive to load-dependent, muscle-specific neuromuscular adaptations and suggest reductions in neuromuscular activation to produce the same absolute submaximal torques after training with high, but not low loads.

Original languageEnglish (US)
Pages (from-to)3265-3269
Number of pages5
JournalJournal of strength and conditioning research
Issue number11
StatePublished - Nov 1 2021


  • mechanomyography
  • motor unit behavior
  • resistance exercise
  • skeletal muscle

ASJC Scopus subject areas

  • Physical Therapy, Sports Therapy and Rehabilitation
  • Orthopedics and Sports Medicine


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