Merkel cell carcinoma: Clinical practice guidelines in oncology™

Stanley J. Miller, Murad Alam, James Andersen, Daniel Berg, Christopher K. Bichakjian, Glen Bowen, Richard T. Cheney, Frank Glass, Roy C. Grekin, James M. Grichnik, Timothy M. Johnson, Anne Kessinger, Nancy Y. Lee, Stuart Lessin, Daniel D. Lydiatt, Lawrence W. Margolis, Kishwer S. Nehal, Paul Nghiem, Allan R. Oseroff, E. William RosenbergAshok R. Shaha, Ronald J. Siegle

Research output: Contribution to journalReview article

17 Scopus citations

Abstract

Merkel cell carcinoma (MCC) is a rare, aggressive cutaneous tumor that combines the local recurrence rates of infiltrative non-melanoma skin cancer with the regional and distant metastatic rates of thick melanoma. The mortality rate of MCC exceeds that of melanoma, and the 5-year disease-specific survival rate is 64%. These guidelines and most biomedical literature suggest that the workup of a patient with MCC should include chest radiograph and additional studies as clinically indicated. These guidelines, which the NCCN Non-Melanoma Skin Cancer Panel developed as a supplement to those for squamous cell and basal cell skin cancer, also outline treatment strategies.

Original languageEnglish (US)
Pages (from-to)704-712
Number of pages9
JournalJNCCN Journal of the National Comprehensive Cancer Network
Volume4
Issue number7
StatePublished - Aug 2006

Keywords

  • Merkel cell carcinoma
  • NCCN Clinical Practice Guidelines
  • Neuroendocrine sarcoma
  • Nonmelanoma skin cancer
  • Sentinel lymph node biopsy

ASJC Scopus subject areas

  • Oncology

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  • Cite this

    Miller, S. J., Alam, M., Andersen, J., Berg, D., Bichakjian, C. K., Bowen, G., Cheney, R. T., Glass, F., Grekin, R. C., Grichnik, J. M., Johnson, T. M., Kessinger, A., Lee, N. Y., Lessin, S., Lydiatt, D. D., Margolis, L. W., Nehal, K. S., Nghiem, P., Oseroff, A. R., ... Siegle, R. J. (2006). Merkel cell carcinoma: Clinical practice guidelines in oncology™. JNCCN Journal of the National Comprehensive Cancer Network, 4(7), 704-712.