Metal accumulation and transport in the ovary of the lizard Podarcis sicula

Marilisa Riggio, Rosaria Scudiero, Jaekwon Lee, Dennis J. Thiele, Elio Parisi, Silvana Filosa

Research output: Contribution to journalArticlepeer-review


The molecular characterisation of a CTR protein is reported in the ovary of the lizard Podarcis sicula; this protein proves to be homologous with the mammalian high affinity copper transporter CTRL Gene expression assessed by Northern blot hybridisation of RNA from growing ovarian follicles and eggs demonstrated that the transcript accumulated during the oocyte growth and reached the highest levels in ovulated eggs. Analysis of the copper content paralleled the profile of CTR1 mRNA, with a rapid increase of the metal concentration during oocyte maturation. These data suggest that the P. sicula CTR1 protein may function in the uptake and storage of the copper to be used during embryonic development.

Original languageEnglish (US)
Pages (from-to)59-62
Number of pages4
JournalItalian Journal of Zoology
Issue numberSUPPL.2
StatePublished - 2004
Externally publishedYes


  • Copper
  • Copper transporter
  • Oogenesis
  • Zinc

ASJC Scopus subject areas

  • Animal Science and Zoology


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