Metallomics in Fish

Camila Pereira Braga, Jiri Adamec, Pedro de Magalhães Padilha

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Abstract

Metallomics allows the integration of traditionally analytical studies with inorganic and biochemical studies. The study of metallomics in living organisms allows us to obtain information about how the metal ion is distributed and coordinated with proteins, the essentiality and/or toxicity, and the individual concentrations of metal species, thus contributing to elucidation of the physiological and functional aspects of these biomolecules. In this context, several lines of research have appeared in the literature with different terms and approaches. For example, metallomic, which deals with the characterization of the total metal/metalloid species present in an organism; metalloprotein, which deals with the characterization of the total elements present in a specific site of an organism (cellular behavior, protein, metalloprotein); and metallomic, which deals with a more in-depth study of metallome. In this area, information is sought on the interactions and functional connections of metal/metalloid species with genes, proteins, metabolites and other biomolecules of the organism and, therefore, the elucidation of the biological role exerted by the metal ions bound to the biomolecules. In this chapter, we will describe techniques used in animal studies.

Original languageEnglish (US)
Title of host publicationAdvances in Experimental Medicine and Biology
PublisherSpringer New York LLC
Pages101-110
Number of pages10
DOIs
StatePublished - 2018

Publication series

NameAdvances in Experimental Medicine and Biology
Volume1055
ISSN (Print)0065-2598
ISSN (Electronic)2214-8019

Keywords

  • Animal
  • Fish
  • Metallomic
  • Metalloprotein

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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