Mexilitene use in pregnancy.

A. R. Gregg, P. G. Tomich

Research output: Contribution to journalArticlepeer-review

20 Scopus citations


Mexilitene, a class 1b antiarrhythmic, was used throughout an entire pregnancy to treat symptomatic premature ventricular contractions in a patient with mitral valve prolapse. Cord blood and maternal serum mexilitene levels at the time of delivery are given. The following conclusions were reached. (1) Mexilitene may have a future in treating pregnant patients with arrhythmias unresponsive to currently approved antiarrhythmic drugs. (2) Evidence to date has shown no adverse affects in infants of mothers breast-feeding while taking mexilitene. (3) Dosages need to be monitored carefully during pregnancy and the postpartum period to ensure that therapeutic drug levels are maintained.

Original languageEnglish (US)
Pages (from-to)33-35
Number of pages3
JournalJournal of perinatology : official journal of the California Perinatal Association
Issue number1
StatePublished - Dec 1988
Externally publishedYes

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology


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