microRNA biogenesis, degradation and activity in plants

Meng Xie, Shuxin Zhang, Bin Yu

Research output: Contribution to journalReview articlepeer-review

74 Scopus citations


microRNAs (miRNAs) are important regulators of gene expression. After excised from primary miRNA transcript by dicer-like1 (DCL1, an RNAse III enzyme), miRNAs bind and guide their effector protein named argonaute 1 (AGO1) to silence the expression of target RNAs containing their complementary sequences in plants. miRNA levels and activities are tightly controlled to ensure their functions in various biological processes such as development, metabolism and responses to abiotic and biotic stresses. Studies have identified many factors that involve in miRNA accumulation and activities. Characterization of these factors in turn greatly improves our understanding of the processes related to miRNAs. Here, we review recent progress of mechanisms underlying miRNA expression and functions in plants.

Original languageEnglish (US)
Pages (from-to)87-99
Number of pages13
JournalCellular and Molecular Life Sciences
Issue number1
StatePublished - Jan 1 2015


  • Biogenesis
  • Plants
  • Target cleavage
  • Translational inhibition
  • Turn over
  • microRNA

ASJC Scopus subject areas

  • Molecular Medicine
  • Molecular Biology
  • Pharmacology
  • Cellular and Molecular Neuroscience
  • Cell Biology


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