Microsporidial stromal keratitis and endophthalmitis in an immunocompetent patient

Arjun B. Sood, Matthew R. Debiec, Steven Yeh, Hans E. Grossniklaus, J. Bradley Randleman

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Purpose: The purpose of this study is to report a case of microsporidial endophthalmitis after penetrating keratoplasty in a healthy patient and discuss the management. Methods: This is a case report. Results: A 69-year-old healthy male underwent penetrating keratoplasty for corneal scar secondary to herpes stromal keratitis. He presented with features of acute graft rejection 3 years later. After failure of medical management, a repeat full thickness keratoplasty was performed. Pathologic examination of the corneal specimen showed microsporidia. The patient then developed a chronic endophthalmitis, and a vitreous tap and injection followed by pars plana vitrectomy were performed. Pathologic examination of tissue showed microsporidia. Conclusions: Microsporidia are being increasingly identified as the cause of stromal keratitis. This is the first report of microsporidial endophthalmitis in a patient without underlying systemic illness.

Original languageEnglish (US)
Article number30
JournalJournal of Ophthalmic Inflammation and Infection
Issue number1
StatePublished - Dec 1 2016
Externally publishedYes

ASJC Scopus subject areas

  • Ophthalmology
  • Infectious Diseases


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