Mitoproteome: Human heart mitochondrial protein sequence database

Purnima Guda, Shankar Subramaniam, Chittibabu Guda

Research output: Chapter in Book/Report/Conference proceedingChapter

12 Scopus citations


The human mitochondrial proteome database has been developed by deriving data from, a combination of public repositories and experimental and computational prediction methods. The experimental data is derived from highly purified mitochondria from, human heart tissue, whereas predictions have been performed by MITOPRED, a genome-scale method for the prediction of nucleus-encoded mitochondrial proteins. Mitochondrial protein sequences from different sources have been clustered to generate a nonredundant dataset. Annotations related to the protein function, structure, disease association, pathways, and so on are collected from a number of public databases using commonly used UNIX and Perl scripts. This chapter provides a detailed description of various data sources and methods used to download, curate, parse, and generate meaningful annotations from, primary as well as derived databases.

Original languageEnglish (US)
Title of host publicationCardiovascular Proteomics
Subtitle of host publicationMethods and Protocols
EditorsFernando Vivanco
Number of pages9
StatePublished - Feb 5 2007
Externally publishedYes

Publication series

NameMethods in Molecular Biology
ISSN (Print)1064-3745


  • Biological database
  • Human heart
  • Mitochondria
  • Mitoproteome

ASJC Scopus subject areas

  • Molecular Biology
  • Genetics


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