Modeling 3-D diffusion using queueing networks

Vahraz Honary, Marissa Nitz, Beata J. Wysocki, Tadeusz A. Wysocki

Research output: Contribution to journalArticlepeer-review

5 Scopus citations


The objective of this paper is to propose and then validate a new method for simulating molecular diffusion in a 3-D environment. Diffusion governing principles of Brownian motion have been discovered by Einstein and Smoluchowski. In a classical approach, diffusion is modeled using partial differential equations. However, solving those, even using numerical methods is usually time consuming, particularly in the case of an inhomogeneous environment. In this paper, we propose to use queueing networks to model diffusion of molecules as governed by Fick's law. The proposed model has been validated using the Kolmogorov-Smirnov test to compare results obtained from a simulation with theoretical standard deviations resulting from Einstein-Smoluchowski's approach.

Original languageEnglish (US)
Pages (from-to)17-23
Number of pages7
StatePublished - May 2019


  • 3-D simulation
  • Brownian motion
  • Diffusion
  • Queuing networks

ASJC Scopus subject areas

  • Statistics and Probability
  • Modeling and Simulation
  • General Biochemistry, Genetics and Molecular Biology
  • Applied Mathematics


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