Modeling of rhythmic behavior in neutral lipid production due to continuous supply of limited nitrogen: Mutual growth and lipid accumulation in microalgae

Rahul Tevatia; James Allen; Paul Blum; Yaşar Demirel; Paul Black

doi:10.1016/j.biortech.2014.07.043

Modeling of rhythmic behavior in neutral lipid production due to continuous supply of limited nitrogen: Mutual growth and lipid accumulation in microalgae

Rahul Tevatia, James Allen, Paul Blum, Yaşar Demirel, Paul Black

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

The relative effects of three precise nitrogen limitation regimes on green micro-algae were assessed using the Trebouxiophycean alga Coccomyxa subellipsoidea grown in a chemostatic bioreactor system. The data provides further evidence that growth and triglyceride (TAG) accumulation are concurrent and independently proportional to the degree of nitrogen limitation in algae. Additionally, TAG accumulation was observed to proceed via oscillations with respect to time and percent dry weight quantity. The predator-prey model was applied to fit the experimental data and to obtain the physiological significance of these oscillations. The results determine the conditions of maximum neutral lipid productivity with respect to nitrate stress and highlight an area of potential future research.

Original language	English (US)
Pages (from-to)	152-159
Number of pages	8
Journal	Bioresource Technology
Volume	170
DOIs	https://doi.org/10.1016/j.biortech.2014.07.043
State	Published - Oct 2014

Keywords

Continuous nitrogen limitation
Maximum productivities
Microalgal growth
Neutral lipid accumulation
Prey-predator model

ASJC Scopus subject areas

Bioengineering
Environmental Engineering
Renewable Energy, Sustainability and the Environment
Waste Management and Disposal

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10.1016/j.biortech.2014.07.043

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title = "Modeling of rhythmic behavior in neutral lipid production due to continuous supply of limited nitrogen: Mutual growth and lipid accumulation in microalgae",

abstract = "The relative effects of three precise nitrogen limitation regimes on green micro-algae were assessed using the Trebouxiophycean alga Coccomyxa subellipsoidea grown in a chemostatic bioreactor system. The data provides further evidence that growth and triglyceride (TAG) accumulation are concurrent and independently proportional to the degree of nitrogen limitation in algae. Additionally, TAG accumulation was observed to proceed via oscillations with respect to time and percent dry weight quantity. The predator-prey model was applied to fit the experimental data and to obtain the physiological significance of these oscillations. The results determine the conditions of maximum neutral lipid productivity with respect to nitrate stress and highlight an area of potential future research.",

keywords = "Continuous nitrogen limitation, Maximum productivities, Microalgal growth, Neutral lipid accumulation, Prey-predator model",

author = "Rahul Tevatia and James Allen and Paul Blum and Ya{\c s}ar Demirel and Paul Black",

note = "Funding Information: This research was supported by a grant from the Department of Energy National Science Foundation (EPSCOR) (grant number: DE-FG36-08GO88055 ), and Office of Research and Economic Development, University of Nebraska, Lincoln, NE ). We acknowledge University of Nebraska-Lincoln Cell Development Facility for funds supporting the research.",

year = "2014",

month = oct,

doi = "10.1016/j.biortech.2014.07.043",

language = "English (US)",

volume = "170",

pages = "152--159",

journal = "Bioresource Technology",

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T2 - Mutual growth and lipid accumulation in microalgae

AU - Tevatia, Rahul

AU - Allen, James

AU - Blum, Paul

AU - Demirel, Yaşar

AU - Black, Paul

N1 - Funding Information: This research was supported by a grant from the Department of Energy National Science Foundation (EPSCOR) (grant number: DE-FG36-08GO88055 ), and Office of Research and Economic Development, University of Nebraska, Lincoln, NE ). We acknowledge University of Nebraska-Lincoln Cell Development Facility for funds supporting the research.

PY - 2014/10

Y1 - 2014/10

N2 - The relative effects of three precise nitrogen limitation regimes on green micro-algae were assessed using the Trebouxiophycean alga Coccomyxa subellipsoidea grown in a chemostatic bioreactor system. The data provides further evidence that growth and triglyceride (TAG) accumulation are concurrent and independently proportional to the degree of nitrogen limitation in algae. Additionally, TAG accumulation was observed to proceed via oscillations with respect to time and percent dry weight quantity. The predator-prey model was applied to fit the experimental data and to obtain the physiological significance of these oscillations. The results determine the conditions of maximum neutral lipid productivity with respect to nitrate stress and highlight an area of potential future research.

AB - The relative effects of three precise nitrogen limitation regimes on green micro-algae were assessed using the Trebouxiophycean alga Coccomyxa subellipsoidea grown in a chemostatic bioreactor system. The data provides further evidence that growth and triglyceride (TAG) accumulation are concurrent and independently proportional to the degree of nitrogen limitation in algae. Additionally, TAG accumulation was observed to proceed via oscillations with respect to time and percent dry weight quantity. The predator-prey model was applied to fit the experimental data and to obtain the physiological significance of these oscillations. The results determine the conditions of maximum neutral lipid productivity with respect to nitrate stress and highlight an area of potential future research.

KW - Continuous nitrogen limitation

KW - Maximum productivities

KW - Microalgal growth

KW - Neutral lipid accumulation

KW - Prey-predator model

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JO - Bioresource Technology

JF - Bioresource Technology

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Modeling of rhythmic behavior in neutral lipid production due to continuous supply of limited nitrogen: Mutual growth and lipid accumulation in microalgae

Abstract

Keywords

ASJC Scopus subject areas

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