Molecular basis for a direct interaction between the Syk protein-tyrosine kinase and phosphoinositide 3-kinase

Keyphrases

• Phosphoinositide 3-kinase (PI3K) 100%
• Direct Interaction 100%
• SH2 Domain 100%
• Tyrosine Kinase 100%
• Binding Site 66%
• Tyrosine 66%
• Phosphotyrosine 66%
• Src Kinase 66%
• Binding Partners 33%
• Phagocytosis 33%
• Ligand-binding Domain 33%
• B Cell Receptor 33%
• Regulatory Subunit 33%
• Yeast Two-hybrid Screen 33%
• Downstream Effectors 33%
• C-Cbl 33%
• Phosphotyrosine Binding Domains 33%
• Molecular Modeling Studies 33%
• Heterologous System 33%
• Docking Site 33%

Biochemistry, Genetics and Molecular Biology

• Phosphoinositide 3-Kinase 100%
• Syk 100%
• Janus Kinase 1 100%
• SH2 Domain 75%
• Binding Site 50%
• C-Terminus 50%
• Tyrosine 50%
• Receptor Tyrosine Kinase 50%
• Molecular Model 25%
• Molecular Modeling 25%
• Tyrosine Kinase 25%
• Binding Domain 25%
• Phagocytosis 25%
• B-Cell Receptor 25%
• Yeast Two-Hybrid Screening 25%
• Src Family Kinase 25%
• Phosphotyrosine-Binding Domain 25%