Molecular communication model of nanoparticle-body interactions in Particulate Drug Delivery Systems

Youssef Chahibi; Massimiliano Pierobon; Sang Ok Song

doi:10.1109/ACSSC.2013.6810452

Molecular communication model of nanoparticle-body interactions in Particulate Drug Delivery Systems

Youssef Chahibi, Massimiliano Pierobon, Sang Ok Song

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

4 Scopus citations

Abstract

Existing work in pharmacokinetics, the study of the movement of drugs in the body, has largely focused on multicompartmental models, based on ordinary first-order equations with constant flow. Nano-scale Particulate Drug Delivery Systems (PDDS) require better computational models. PDDS has been previously abstracted by the same authors as Molecular Communication (MC) systems, by solving the advection-diffusion problem with time-varying flow. In this paper, this framework is extended to solve the nanoparticle-body interactions problem. The delay and path loss of the system are expressed analytically. The results are validated by finite-element simulations. This model will enable more thorough pharmacokinetics than multicompartmental models.

Original language	English (US)
Title of host publication	Conference Record of the 47th Asilomar Conference on Signals, Systems and Computers
Publisher	IEEE Computer Society
Pages	1051-1055
Number of pages	5
ISBN (Print)	9781479923908
DOIs	https://doi.org/10.1109/ACSSC.2013.6810452
State	Published - 2013
Event	2013 47th Asilomar Conference on Signals, Systems and Computers - Pacific Grove, CA, United States Duration: Nov 3 2013 → Nov 6 2013

Publication series

Name	Conference Record - Asilomar Conference on Signals, Systems and Computers
ISSN (Print)	1058-6393

Other

Other	2013 47th Asilomar Conference on Signals, Systems and Computers
Country/Territory	United States
City	Pacific Grove, CA
Period	11/3/13 → 11/6/13

ASJC Scopus subject areas

Signal Processing
Computer Networks and Communications

Access to Document

10.1109/ACSSC.2013.6810452

Cite this

Chahibi, Y., Pierobon, M., & Song, S. O. (2013). Molecular communication model of nanoparticle-body interactions in Particulate Drug Delivery Systems. In Conference Record of the 47th Asilomar Conference on Signals, Systems and Computers (pp. 1051-1055). Article 6810452 (Conference Record - Asilomar Conference on Signals, Systems and Computers). IEEE Computer Society. https://doi.org/10.1109/ACSSC.2013.6810452

Molecular communication model of nanoparticle-body interactions in Particulate Drug Delivery Systems. / Chahibi, Youssef; Pierobon, Massimiliano; Song, Sang Ok.
Conference Record of the 47th Asilomar Conference on Signals, Systems and Computers. IEEE Computer Society, 2013. p. 1051-1055 6810452 (Conference Record - Asilomar Conference on Signals, Systems and Computers).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Chahibi, Y, Pierobon, M & Song, SO 2013, Molecular communication model of nanoparticle-body interactions in Particulate Drug Delivery Systems. in Conference Record of the 47th Asilomar Conference on Signals, Systems and Computers., 6810452, Conference Record - Asilomar Conference on Signals, Systems and Computers, IEEE Computer Society, pp. 1051-1055, 2013 47th Asilomar Conference on Signals, Systems and Computers, Pacific Grove, CA, United States, 11/3/13. https://doi.org/10.1109/ACSSC.2013.6810452

Chahibi Y, Pierobon M, Song SO. Molecular communication model of nanoparticle-body interactions in Particulate Drug Delivery Systems. In Conference Record of the 47th Asilomar Conference on Signals, Systems and Computers. IEEE Computer Society. 2013. p. 1051-1055. 6810452. (Conference Record - Asilomar Conference on Signals, Systems and Computers). doi: 10.1109/ACSSC.2013.6810452

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Molecular communication model of nanoparticle-body interactions in Particulate Drug Delivery Systems

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