Molecular correlates of spontaneous activity in non-human primates

Amanda C. Mitchell; Georgina Aldridge; Shawn Kohler; Greg Stanton; Elinor Sullivan; Krassimira Garbett; Gabor Faludi; Károly Mirnics; Judy L. Cameron; William Greenough

doi:10.1007/s00702-010-0483-7

Molecular correlates of spontaneous activity in non-human primates

Amanda C. Mitchell, Georgina Aldridge, Shawn Kohler, Greg Stanton, Elinor Sullivan, Krassimira Garbett, Gabor Faludi, Károly Mirnics, Judy L. Cameron, William Greenough

Research output: Contribution to journal › Article

4 Scopus citations

Abstract

In our monkey model, cortical ARC and BDNF expressions were strongly correlated with spontaneous physical activity. The expressions of ARC and BDNF were inversely correlated with serum CRP levels, suggesting that CRP could be a putative peripheral marker of brain resiliency.

Original language	English (US)
Pages (from-to)	1353-1358
Number of pages	6
Journal	Journal of Neural Transmission
Volume	117
Issue number	12
DOIs	https://doi.org/10.1007/s00702-010-0483-7
State	Published - Dec 2010

Keywords

ARC
BDNF
CRP
Gene expression
Motor cortex
Physical activity

ASJC Scopus subject areas

Neurology
Clinical Neurology
Psychiatry and Mental health
Biological Psychiatry

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Mitchell, A. C., Aldridge, G., Kohler, S., Stanton, G., Sullivan, E., Garbett, K., Faludi, G., Mirnics, K., Cameron, J. L., & Greenough, W. (2010). Molecular correlates of spontaneous activity in non-human primates. Journal of Neural Transmission, 117(12), 1353-1358. https://doi.org/10.1007/s00702-010-0483-7

Molecular correlates of spontaneous activity in non-human primates. / Mitchell, Amanda C.; Aldridge, Georgina; Kohler, Shawn; Stanton, Greg; Sullivan, Elinor; Garbett, Krassimira; Faludi, Gabor; Mirnics, Károly; Cameron, Judy L.; Greenough, William.

In: Journal of Neural Transmission, Vol. 117, No. 12, 12.2010, p. 1353-1358.

Research output: Contribution to journal › Article

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