Molecular correlates of spontaneous activity in non-human primates

Amanda C. Mitchell, Georgina Aldridge, Shawn Kohler, Greg Stanton, Elinor Sullivan, Krassimira Garbett, Gabor Faludi, Károly Mirnics, Judy L. Cameron, William Greenough

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

In our monkey model, cortical ARC and BDNF expressions were strongly correlated with spontaneous physical activity. The expressions of ARC and BDNF were inversely correlated with serum CRP levels, suggesting that CRP could be a putative peripheral marker of brain resiliency.

Original languageEnglish (US)
Pages (from-to)1353-1358
Number of pages6
JournalJournal of Neural Transmission
Volume117
Issue number12
DOIs
StatePublished - Dec 2010

Keywords

  • ARC
  • BDNF
  • CRP
  • Gene expression
  • Motor cortex
  • Physical activity

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology
  • Psychiatry and Mental health
  • Biological Psychiatry

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  • Cite this

    Mitchell, A. C., Aldridge, G., Kohler, S., Stanton, G., Sullivan, E., Garbett, K., Faludi, G., Mirnics, K., Cameron, J. L., & Greenough, W. (2010). Molecular correlates of spontaneous activity in non-human primates. Journal of Neural Transmission, 117(12), 1353-1358. https://doi.org/10.1007/s00702-010-0483-7