TY - JOUR
T1 - Molecular mechanisms of cell death and regeneration in acute ischemic renal injury
AU - Padanilam, Babu J.
AU - Lewington, Andrew J.P.
PY - 1999
Y1 - 1999
N2 - Acute renal failure continues to have an unacceptably high mortality rate. Ischemic renal injury is the most common cause of acute renal failure. Understanding the molecular mechanisms of cell death and regeneration is important for designing future therapeutic strategies. Recent interest in our laboratory has focused on molecular response after ischemic renal injury and, in particular, genes that are important in cell death and repair after ischemia. The identification of genes that are differentially expressed after ischemia has led to new information regarding the identity of possible mediators of cell death and regeneration in renal tubular epithelial cells.
AB - Acute renal failure continues to have an unacceptably high mortality rate. Ischemic renal injury is the most common cause of acute renal failure. Understanding the molecular mechanisms of cell death and regeneration is important for designing future therapeutic strategies. Recent interest in our laboratory has focused on molecular response after ischemic renal injury and, in particular, genes that are important in cell death and repair after ischemia. The identification of genes that are differentially expressed after ischemia has led to new information regarding the identity of possible mediators of cell death and regeneration in renal tubular epithelial cells.
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U2 - 10.1097/00041552-199901000-00004
DO - 10.1097/00041552-199901000-00004
M3 - Review article
C2 - 9914856
AN - SCOPUS:0032956878
SN - 1062-4821
VL - 8
SP - 15
EP - 19
JO - Current opinion in nephrology and hypertension
JF - Current opinion in nephrology and hypertension
IS - 1
ER -