Monitoring osteogenesis using high resolution magnetic resonance imaging

Huihui Xu, Shadi F. Othman, Liu Hong, Richard L. Magin

Research output: Chapter in Book/Report/Conference proceedingConference contribution


There is a critical need in bone tissue engineering for a noninvasive monitor of the progression of osteogenesis. In this work, an MR microscopy system was used to study over a 4-week period the growth and development of in vitro tissue engineered constructs fabricated by seeding human mesenchymal stems cells onto gelatin sponge matrices. Our preliminary data demonstrate progressive reduction in all these parameters with time of incubation, which correlates well with MRI image contrast and consecutive biochemical changes. This study suggests that MR microscopy can be effective in the in vitro evaluation and visualization of osteogenic constructs.

Original languageEnglish (US)
Title of host publicationProceedings of the 2005 Summer Bioengineering Conference, 2005 SBC
Number of pages2
StatePublished - 2005
Event2005 Summer Bioengineering Conference - Vail, CO, United States
Duration: Jun 22 2005Jun 26 2005

Publication series

NameProceedings of the 2005 Summer Bioengineering Conference


Conference2005 Summer Bioengineering Conference
Country/TerritoryUnited States
CityVail, CO

ASJC Scopus subject areas

  • General Engineering


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