Multiaxial mechanical behavior of the porcine anterior lens capsule

M. R. Heistand, R. M. Pedrigi, S. L. Delange, J. Dziezyc, J. D. Humphrey

Research output: Contribution to journalArticle

18 Scopus citations

Abstract

The biomechanics of the lens capsule of the eye is important both in physiologic processes such as accommodation and clinical treatments such as cataract surgery. Although the lens capsule experiences multiaxial stresses in vivo, there have been no measurements of its multiaxial properties or possible regional heterogeneities. Rather all prior mechanical data have come from 1-D pressure-volume or uniaxial force-length tests. Here, we report a new experimental approach to study in situ the regional, multiaxial mechanical behavior of the lens capsule. Moreover, we report multiaxial data suggesting that the porcine anterior lens capsule exhibits a typical nonlinear pseudoelastic behavior over finite strains, that the in situ state is pre-stressed multiaxially, and that the meridional and circumferential directions are principal directions of strain, which is nearly equibiaxial at the pole but less so towards the equator. Such data are fundamental to much needed constitutive formulations.

Original languageEnglish (US)
Pages (from-to)168-177
Number of pages10
JournalBiomechanics and Modeling in Mechanobiology
Volume4
Issue number2-3
DOIs
StatePublished - Nov 2005

Keywords

  • Accommodation
  • Biomechanics
  • Cataracts
  • Stiffness
  • Stress

ASJC Scopus subject areas

  • Biotechnology
  • Modeling and Simulation
  • Mechanical Engineering

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