@article{4a8057d741f34780a4e98f75c7f12647,
title = "Multiple antimutagenesis mechanisms affect mutagenic activity and specificity of the base analog 6-N-hydroxylaminopurine in bacteria and yeast",
abstract = "Base analog 6-N-hydroxylaminopurine is a potent mutagen in variety of prokaryotic and eukaryotic organisms. In the review, we discuss recent results of the studies of HAP mutagenic activity, genetic control and specificity in bacteria and yeast with the emphasis to the mechanisms protecting living cells from mutagenic and toxic effects of this base analog.",
keywords = "6-N-hydroxylaminopurine, Antimutagenesis, DNA replication fidelity, Mutagenic specificity, Nucleic acid base analog, Purine biosynthesis",
author = "Kozmin, {Stanislav G.} and Schaaper, {Roel M.} and Shcherbakova, {Polina V.} and Kulikov, {Vladimir N.} and Noskov, {Vladimir N.} and Guetsova, {Maria L.} and Alenin, {Vladimir V.} and Rogozin, {Igor B.} and Makarova, {Kira S.} and Pavlov, {Youri I.}",
note = "Funding Information: We are grateful to Prof. H. Mori (Nara Institute of Science and Technology) for providing unpublished sequencing data of E. coli chromosome and Dr. Bertrand Daignan-Fornier (IBGC, Bordeuax, France) for his permission to use some of his unpublished plasmids and yeast strains. We are grateful to Prof. E.I. Budowski, Prof. H. Hayatsu and Prof. H. Araki for valuable discussions, Prof. N.N. Khromov-Bori-sov (Centro de Biotechnologia, Universidade Porto Allegre, Brazil) for suggestions, to Drs. J. Drake and Tran Tuan Hiep (NIEHS) for optA strain and msh2 disruption plasmids, respectively, to Drs. V. Domkin and A. Zekhnov for the strain with ade12-1 mutation, to Y. Andreichuk for the plasmids with ade2 and ade6 genes disruptions. Y.I.P. is grateful to Prof. A. Sugino for creative atmosphere during sabbatical in his laboratory in Osaka in 1996–1997 (Y.I. Pavlov was supported by JSPS award). I.B. Rogozin was supported by the Russian Fund of Fundamental Research (RFFR grant N 96-04-49957). V.N. Noskov and Y.I. Pavlov were supported by RFFR grants 97-04-49-719 and 95-04-11583, respectively.",
year = "1998",
month = jun,
day = "18",
doi = "10.1016/S0027-5107(97)00280-7",
language = "English (US)",
volume = "402",
pages = "41--50",
journal = "Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis",
issn = "0027-5107",
publisher = "Elsevier BV",
number = "1-2",
}