TY - JOUR
T1 - Multiple subpial cortical transaction (MST) for the treatment of extensive seizure foci
AU - Patil, Arun Angelo
AU - Andrews, Richard
AU - Torkelson, Richard
PY - 1997
Y1 - 1997
N2 - Multiple subpial transaction (MST) was used to treat 7 patients who had intractable epilepsy with extensive seizure foci involving more than one lobe and both hemispheres, and who have had a follow-up of at least 2 years. The longest follow-up is 61 months, with a median of 43 months. Preoperative investigations included magnetic resonance scans, positron emission tomography scans, single photon emission computed tomography scans, and video-EEG monitoring with scalp and subdural electrodes. Two patients' seizure foci were in both hemispheres, and 5 patients' foci were in 2 lobes of 1 hemisphere. The motor cortex was involved in 5 patients and the speech areas in 1 patient. MST at an interval of 4 mm was performed over all areas that showed seizure foci. Two patients are free of seizures, 1 patient is free of seizures involving the operated hemisphere, 1 has rare seizures, 1 has >90% reduction in seizure frequency, 1 has >70% reduction in seizure frequency, and 1 did not respond to MST. MST alone was able to control seizures to varying degrees, without producing a permanent deficit, in 84% of patients with intractable seizures originating from large areas of the cortex.
AB - Multiple subpial transaction (MST) was used to treat 7 patients who had intractable epilepsy with extensive seizure foci involving more than one lobe and both hemispheres, and who have had a follow-up of at least 2 years. The longest follow-up is 61 months, with a median of 43 months. Preoperative investigations included magnetic resonance scans, positron emission tomography scans, single photon emission computed tomography scans, and video-EEG monitoring with scalp and subdural electrodes. Two patients' seizure foci were in both hemispheres, and 5 patients' foci were in 2 lobes of 1 hemisphere. The motor cortex was involved in 5 patients and the speech areas in 1 patient. MST at an interval of 4 mm was performed over all areas that showed seizure foci. Two patients are free of seizures, 1 patient is free of seizures involving the operated hemisphere, 1 has rare seizures, 1 has >90% reduction in seizure frequency, 1 has >70% reduction in seizure frequency, and 1 did not respond to MST. MST alone was able to control seizures to varying degrees, without producing a permanent deficit, in 84% of patients with intractable seizures originating from large areas of the cortex.
KW - Epilepsy
KW - Extratemporal epilepsy
KW - Multiple subpial transection
KW - Surgery
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U2 - 10.1016/s0896-6974(97)00019-4
DO - 10.1016/s0896-6974(97)00019-4
M3 - Article
AN - SCOPUS:0030790974
SN - 0896-6974
VL - 10
SP - 198
EP - 202
JO - Journal of Epilepsy
JF - Journal of Epilepsy
IS - 4
ER -